Who can I contact with regards to mental health-related help/advice?
If you or anyone you know, is in need of mental health assistance, please dont hesitate to contact The South African Depression and Anxiety Group (http://www.sadag.org). You can also contact the Mental Health Information Centre (http://www.mentalhealthsa.co.za).
When will I be able to take part in the study?
You can already register and create a personalised login. However, we are still finalising some details for this study, and we plan to launch the project early 2019. If you have created a login, you will receive an email to inform you that you can fill in the questionnaires send us your stool sample.
Are there any risks in taking part in this study?
This study will use non-invasive stool collection protocols, with no known risks associated with it. Some of the questionnaires ask questions about previous stressful life events, therefore certain individuals could feel distressed or anxious when answering these questions. Our informed consent document states that if you experience any distress during the study, that you should contact the principal investigator, and they will refer you to the Mental Health Information Centre (http://www.mentalhealthsa.co.za) for further assistance.
Will I receive a psychiatric diagnosis based on my questionnaire data?
No, the questionnaires we use cannot be used to provide clinical diagnoses of psychiatric conditions. These questionnaires will be used to determine whether you experience PTSD/anxiety/depressive symptoms. You will receive general referral information should you wish to seek professional mental health assistance.
Would my data be kept confidential?
Yes, your data will be de-identified so that researchers working with the data will not know who you are. Only the principal research investigator will have access to participant names
Who has access to my data?
Researchers working on The South African Microbiome Initiative in Neuroscience will have access to your data, however, they will not see your name, only your laboratory identification number.
Will I receive personalised feedback about my gut microbiome or questionnaires?
Not as part of the study, but it can be provided at a cost. Due to the large number of participants that will be enrolled in the study, we will not be able to send personalised feedback. However, should you wish to receive personalised feedback, that could be provided for a fee (to cover expenses relating to constructing a feedback report). Please contact us at firstname.lastname@example.org to find out more about pricing.
How will this study help me?
The aim of this study is to determine how gut microbes are associated with depression, anxiety and stress disorders by using large sample groups. The study will not be able to make conclusions for individuals, but will rather be able to report on overall findings of the entire group of participants. Although there is no direct benefit to you, this study will help researchers better understand how gut microbes influence mental health and future studies could use these findings to design treatments (such as specially formulated pre- and probiotic supplements) to help alleviate the symptoms of these disorders. The overall findings of this study will be communicated to study participants.
Would I receive any payment for taking part in the study?
You will receive a R100 Pick & Pay voucher to compensate you for the time you have invested to take part in our study.
What happens to my stool sample once you receive it?
Once we receive your stool sample in the laboratory, it is stored in freezers until researchers can extract DNA from it. During the DNA extraction procedure, the researcher uses a laboratory protocol in order to get all the DNA from the bacteria in your stool sample. This DNA is then sent to a company to determine the sequences of the DNA of the bacteria in your stool sample. The company sends us the sequencing data, which we use to do analyses to determine which factors (such as diet, stress, sleep, disease etc.) affect your gut microbiome composition. Your data is kept confidential and only the principal investigator of the study has access to your name since all samples receive a unique study laboratory ID in order to maintain confidentiality.